Yes, but it's often misunderstood. True moon face, or what people refer to as "cortisol face," is a real medical condition often caused by Cushing’s Syndrome, which occurs when the body produces too much cortisol—typically due to a pituitary tumor or prolonged steroid use (like prednisone). It can also appear in conditions like hypothyroidism.

However, Cushing’s Syndrome is rare, affecting only 10 to 15 people per million annually. Most cases of a rounder, fuller face are not due to high cortisol, but instead linked to weight gain, diet, lifestyle, and genetics.

What Contributes to a Cortisol-Like Face?

• Medical Causes: Cushing’s Syndrome, hypothyroidism.
• Medications: Long-term steroid use can lead to fluid retention and facial swelling.
• Lifestyle Factors: Poor sleep, chronic stress, processed foods, caffeine, and lack of exercise can elevate cortisol—but usually not enough alone to cause “moon face.”
• Stress: Chronic stress may increase cortisol slightly but is unlikely to be the sole cause of facial changes.

Can You Tell Just By Looking?

No. According to experts, you can’t diagnose high cortisol just by looking at someone’s face. If you're concerned, the best course of action is to consult a primary care physician or endocrinologist who can order proper testing (blood, saliva, or urine).

How to Address It?

If your cortisol is truly elevated, lowering it takes time and should be guided by a physician. Do not self-diagnose or stop medications without medical supervision. Instead, focus on proven strategies:

• Stress management
• Balanced nutrition
• Exercise
• Sleep hygiene

But remember: most often, a rounder face is not a hormonal issue—and assuming it is can lead to unnecessary anxiety.